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Impact of serum-free media on the expansion and functionality of CD19.CAR T-cells

Fetal bovine serum (FBS) or human serum is widely used in the production of chimeric antigen receptor (CAR) T-cells. In order to overcome a lot-to-lot inconsistency, the use of chemically defined medium that is free of animal-components would be highly desirable. The present study compared three ser...

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Detalles Bibliográficos
Autores principales: Eberhardt, Franziska, Hückelhoven-Krauss, Angela, Kunz, Alexander, Jiang, Genqiao, Sauer, Tim, Reichman, Avinoam, Neuber, Brigitte, Böpple, Kathrin, Schmitt, Anita, Müller-Tidow, Carsten, Schmitt, Michael, Keib, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249581/
https://www.ncbi.nlm.nih.gov/pubmed/37264971
http://dx.doi.org/10.3892/ijmm.2023.5261