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Meta-Analysis of Keratoconus Transcriptomic Data Revealed Altered RNA Editing Levels Impacting Keratin Genomic Clusters

INTRODUCTION: Keratoconus (KC) is an ocular disorder with a multifactorial origin. Transcriptomic analyses (RNA-seq) revealed deregulations of coding (mRNA) and non-coding RNAs (ncRNAs) in KC, suggesting that mRNA-ncRNA co-regulations can promote the onset of KC. The present study investigates the m...

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Detalles Bibliográficos
Autores principales: Bortoletto, Enrico, Pieretti, Fabio, Brun, Paola, Venier, Paola, Leonardi, Andrea, Rosani, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249681/
https://www.ncbi.nlm.nih.gov/pubmed/37279397
http://dx.doi.org/10.1167/iovs.64.7.12