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Eltrombopag Preserves the Clonogenic Potential of Hematopoietic Stem Cells During Treatment With Antithymocyte Globulin in Patients With Aplastic Anemia

Aplastic anemia (AA) is frequently caused by a T-cell mediated autoimmune depletion of the hematopoietic stem and progenitor cell (HSPC) compartment. Immunosuppressive therapy (IST) with antithymocyte globulin (ATG) and cyclosporine represents the first-line treatment of AA. One side effect of ATG t...

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Detalles Bibliográficos
Autores principales: Vieri, Margherita, Rolles, Benjamin, Crocioni, Maria, Schemionek-Reinders, Mirle, Isfort, Susanne, Panse, Jens, Brümmendorf, Tim H., Beier, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249716/
https://www.ncbi.nlm.nih.gov/pubmed/37304936
http://dx.doi.org/10.1097/HS9.0000000000000906