Computational simulations of tumor growth and treatment response: Benefits of high-frequency, low-dose drug regimens and concurrent vascular normalization

Implementation of effective cancer treatment strategies requires consideration of how the spatiotemporal heterogeneities within the tumor microenvironment (TME) influence tumor progression and treatment response. Here, we developed a multi-scale three-dimensional mathematical model of the TME to sim...

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Detalles Bibliográficos
Autores principales: Nikmaneshi, Mohammad R., Jain, Rakesh K., Munn, Lance L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249820/
https://www.ncbi.nlm.nih.gov/pubmed/37289729
http://dx.doi.org/10.1371/journal.pcbi.1011131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249820/
https://www.ncbi.nlm.nih.gov/pubmed/37289729
http://dx.doi.org/10.1371/journal.pcbi.1011131

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