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Copper ions inhibit pentose phosphate pathway function in Staphylococcus aureus

To gain a better insight of how Copper (Cu) ions toxify cells, metabolomic analyses were performed in S. aureus strains that lacks the described Cu ion detoxification systems (ΔcopBL ΔcopAZ; cop(-)). Exposure of the cop(-) strain to Cu(II) resulted in an increase in the concentrations of metabolites...

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Detalles Bibliográficos
Autores principales: Norambuena, Javiera, Al-Tameemi, Hassan, Bovermann, Hannah, Kim, Jisun, Beavers, William N., Skaar, Eric P., Parker, Dane, Boyd, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249872/
https://www.ncbi.nlm.nih.gov/pubmed/37235600
http://dx.doi.org/10.1371/journal.ppat.1011393