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AI-Assisted chemical probe discovery for the understudied Calcium-Calmodulin Dependent Kinase, PNCK

PNCK, or CAMK1b, is an understudied kinase of the calcium-calmodulin dependent kinase family which recently has been identified as a marker of cancer progression and survival in several large-scale multi-omics studies. The biology of PNCK and its relation to oncogenesis has also begun to be elucidat...

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Detalles Bibliográficos
Autores principales: Essegian, Derek J., Chavez, Valery, Khurshid, Rabia, Merchan, Jaime R., Schürer, Stephan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249896/
https://www.ncbi.nlm.nih.gov/pubmed/37235579
http://dx.doi.org/10.1371/journal.pcbi.1010263