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Correlating continuously captured home-based digital biomarkers of daily function with postmortem neurodegenerative neuropathology

BACKGROUND: Outcome measures available for use in Alzheimer’s disease (AD) clinical trials are limited in ability to detect gradual changes. Measures of everyday function and cognition assessed unobtrusively at home using embedded sensing and computing generated “digital biomarkers” (DBs) have been...

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Detalles Bibliográficos
Autores principales: Hantke, Nathan C., Kaye, Jeffrey, Mattek, Nora, Wu, Chao-Yi, Dodge, Hiroko H., Beattie, Zachary, Woltjer, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249904/
https://www.ncbi.nlm.nih.gov/pubmed/37289845
http://dx.doi.org/10.1371/journal.pone.0286812