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Cannabigerol modulates α(2)-adrenoceptor and 5-HT(1A) receptor-mediated electrophysiological effects on dorsal raphe nucleus and locus coeruleus neurons and anxiety behavior in rat

The pharmacological profile of cannabigerol (CBG), which acid form constitutes the main precursor of the most abundant cannabinoids, has been scarcely studied. It has been reported to target α(2-)adrenoceptor and 5-HT(1A) receptor. The locus coeruleus (LC) and the dorsal raphe nucleus (DRN) are the...

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Detalles Bibliográficos
Autores principales: Mendiguren, Aitziber, Aostri, Erik, Rodilla, Irati, Pujana, Iker, Noskova, Ekaterina, Pineda, Joseba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249961/
https://www.ncbi.nlm.nih.gov/pubmed/37305529
http://dx.doi.org/10.3389/fphar.2023.1183019