Characterizing the Blood-Stage Antimalarial Activity of Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum

BACKGROUND: The long-acting 8-aminoquinoline tafenoquine may be a good candidate for mass drug administration if it exhibits sufficient blood-stage antimalarial activity at doses low enough to be tolerated by glucose 6-phosphate dehydrogenase (G6PD)–deficient individuals. METHODS: Healthy adults wit...

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Detalles Bibliográficos
Autores principales: Barber, Bridget E, Abd-Rahman, Azrin N, Webster, Rebecca, Potter, Adam J, Llewellyn, Stacey, Marquart, Louise, Sahai, Nischal, Leelasena, Indika, Birrell, Geoffrey W, Edstein, Michael D, Shanks, G Dennis, Wesche, David, Moehrle, Joerg J, McCarthy, James S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249991/
https://www.ncbi.nlm.nih.gov/pubmed/36795050
http://dx.doi.org/10.1093/cid/ciad075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249991/
https://www.ncbi.nlm.nih.gov/pubmed/36795050
http://dx.doi.org/10.1093/cid/ciad075

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