Mutate and observe: utilizing deep neural networks to investigate the impact of mutations on translation initiation

MOTIVATION: The primary regulatory step for protein synthesis is translation initiation, which makes it one of the fundamental steps in the central dogma of molecular biology. In recent years, a number of approaches relying on deep neural networks (DNNs) have demonstrated superb results for predicti...

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Detalles Bibliográficos
Autores principales: Ozbulak, Utku, Lee, Hyun Jung, Zuallaert, Jasper, De Neve, Wesley, Depuydt, Stephen, Vankerschaver, Joris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250082/
https://www.ncbi.nlm.nih.gov/pubmed/37225409
http://dx.doi.org/10.1093/bioinformatics/btad338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250082/
https://www.ncbi.nlm.nih.gov/pubmed/37225409
http://dx.doi.org/10.1093/bioinformatics/btad338

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