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DHX9-mediated pathway contributes to the malignant phenotype of myelodysplastic syndromes

DHX9 is a member of the DEAH (Asp-Glu-Ala-His) helicase family and regulates DNA replication and RNA processing. DHX9 dysfunction promotes tumorigenesis in several solid cancers. However, the role of DHX9 in MDS is still unknown. Here, we analyzed the expression of DHX9 and its clinical significance...

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Detalles Bibliográficos
Autores principales: Huang, Nanfang, Song, Yang, Shi, Wenhui, Guo, Juan, Zhang, Zheng, He, Qi, Wu, Lingyun, Li, Xiao, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250162/
https://www.ncbi.nlm.nih.gov/pubmed/37305700
http://dx.doi.org/10.1016/j.isci.2023.106962