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HSP90α is needed for the survival of rod photoreceptors and regulates the expression of rod PDE6 subunits

Heat shock protein 90 (HSP90) is an abundant molecular chaperone that regulates the stability of a small set of proteins essential in various cellular pathways. Cytosolic HSP90 has two closely related paralogs: HSP90α and HSP90β. Due to the structural and sequence similarities of cytosolic HSP90 par...

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Detalles Bibliográficos
Autores principales: Munezero, Daniella, Aliff, Hunter, Salido, Ezequiel, Saravanan, Thamaraiselvi, Sanzhaeva, Urikhan, Guan, Tongju, Ramamurthy, Visvanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250166/
https://www.ncbi.nlm.nih.gov/pubmed/37172722
http://dx.doi.org/10.1016/j.jbc.2023.104809