Engineering of NEMO as calcium indicators with large dynamics and high sensitivity

Genetically encoded calcium indicators (GECIs) are indispensable tools for real-time monitoring of intracellular calcium signals and cellular activities in living organisms. Current GECIs face the challenge of suboptimal peak signal-to-baseline ratio (SBR) with limited resolution for reporting subtl...

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Detalles Bibliográficos
Autores principales: Li, Jia, Shang, Ziwei, Chen, Jia-Hui, Gu, Wenjia, Yao, Li, Yang, Xin, Sun, Xiaowen, Wang, Liuqing, Wang, Tianlu, Liu, Siyao, Li, Jiajing, Hou, Tingting, Xing, Dajun, Gill, Donald L., Li, Jiejie, Wang, Shi-Qiang, Hou, Lijuan, Zhou, Yubin, Tang, Ai-Hui, Zhang, Xiaohui, Wang, Youjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250196/
https://www.ncbi.nlm.nih.gov/pubmed/37081094
http://dx.doi.org/10.1038/s41592-023-01852-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250196/
https://www.ncbi.nlm.nih.gov/pubmed/37081094
http://dx.doi.org/10.1038/s41592-023-01852-9

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