Efficient reconstruction of cell lineage trees for cell ancestry and cancer

Mosaic mutations can be used to track cell ancestries and reconstruct high-resolution lineage trees during cancer progression and during development, starting from the first cell divisions of the zygote. However, this approach requires sampling and analyzing the genomes of multiple cells, which can...

Descripción completa

Detalles Bibliográficos
Autores principales: Jang, Yeongjun, Fasching, Liana, Bae, Taejeong, Tomasini, Livia, Schreiner, Jeremy, Szekely, Anna, Fernandez, Thomas V, Leckman, James F, Vaccarino, Flora M, Abyzov, Alexej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250207/
https://www.ncbi.nlm.nih.gov/pubmed/37026484
http://dx.doi.org/10.1093/nar/gkad254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250207/
https://www.ncbi.nlm.nih.gov/pubmed/37026484
http://dx.doi.org/10.1093/nar/gkad254

Ejemplares similares