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Efficient reconstruction of cell lineage trees for cell ancestry and cancer
Mosaic mutations can be used to track cell ancestries and reconstruct high-resolution lineage trees during cancer progression and during development, starting from the first cell divisions of the zygote. However, this approach requires sampling and analyzing the genomes of multiple cells, which can...
Autores principales: | Jang, Yeongjun, Fasching, Liana, Bae, Taejeong, Tomasini, Livia, Schreiner, Jeremy, Szekely, Anna, Fernandez, Thomas V, Leckman, James F, Vaccarino, Flora M, Abyzov, Alexej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250207/ https://www.ncbi.nlm.nih.gov/pubmed/37026484 http://dx.doi.org/10.1093/nar/gkad254 |
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