WDR5 is required for DUX4 expression and its pathological effects in FSHD muscular dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) is one of the most prevalent neuromuscular disorders. The disease is linked to copy number reduction and/or epigenetic alterations of the D4Z4 macrosatellite on chromosome 4q35 and associated with aberrant gain of expression of the transcription factor D...

Descripción completa

Detalles Bibliográficos
Autores principales: Mocciaro, Emanuele, Giambruno, Roberto, Micheloni, Stefano, Cernilogar, Filippo M, Andolfo, Annapaola, Consonni, Cristina, Pannese, Maria, Ferri, Giulia, Runfola, Valeria, Schotta, Gunnar, Gabellini, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250208/
https://www.ncbi.nlm.nih.gov/pubmed/37021550
http://dx.doi.org/10.1093/nar/gkad230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250208/
https://www.ncbi.nlm.nih.gov/pubmed/37021550
http://dx.doi.org/10.1093/nar/gkad230

Ejemplares similares