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UV-DDB stimulates the activity of SMUG1 during base excision repair of 5-hydroxymethyl-2'-deoxyuridine moieties

UV-damaged DNA-binding protein (UV-DDB) is a heterodimeric protein, consisting of DDB1 and DDB2 subunits, that works to recognize DNA lesions induced by UV damage during global genome nucleotide excision repair (GG-NER). Our laboratory previously discovered a non-canonical role for UV-DDB in the pro...

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Detalles Bibliográficos
Autores principales: Jang, Sunbok, Raja, Sripriya J, Roginskaya, Vera, Schaich, Matthew A, Watkins, Simon C, Van Houten, Bennett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250209/
https://www.ncbi.nlm.nih.gov/pubmed/36971122
http://dx.doi.org/10.1093/nar/gkad206