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Role of the 5′ end phosphorylation state for small RNA stability and target RNA regulation in bacteria
In enteric bacteria, several small RNAs (sRNAs) including MicC employ endoribonuclease RNase E to stimulate target RNA decay. A current model proposes that interaction of the sRNA 5′ monophosphate (5′P) with the N-terminal sensing pocket of RNase E allosterically activates cleavage of the base-paire...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250213/ https://www.ncbi.nlm.nih.gov/pubmed/36987877 http://dx.doi.org/10.1093/nar/gkad226 |