The molecular grammar of protein disorder guiding genome-binding locations

Intrinsically disordered regions (IDRs) direct transcription factors (TFs) towards selected genomic occurrences of their binding motif, as exemplified by budding yeast's Msn2. However, the sequence basis of IDR-directed TF binding selectivity remains unknown. To reveal this sequence grammar, we...

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Detalles Bibliográficos
Autores principales: Jonas, Felix, Carmi, Miri, Krupkin, Beniamin, Steinberger, Joseph, Brodsky, Sagie, Jana, Tamar, Barkai, Naama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250222/
https://www.ncbi.nlm.nih.gov/pubmed/36938874
http://dx.doi.org/10.1093/nar/gkad184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250222/
https://www.ncbi.nlm.nih.gov/pubmed/36938874
http://dx.doi.org/10.1093/nar/gkad184

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