Not4-dependent targeting of MMF1 mRNA to mitochondria limits its expression via ribosome pausing, Egd1 ubiquitination, Caf130, no-go-decay and autophagy

The Ccr4–Not complex is a conserved multi protein complex with diverse roles in the mRNA life cycle. Recently we determined that the Not1 and Not4 subunits of Ccr4–Not inversely regulate mRNA solubility and thereby impact dynamics of co-translation events. One mRNA whose solubility is limited by Not...

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Detalles Bibliográficos
Autores principales: Chen, Siyu, Allen, George, Panasenko, Olesya O, Collart, Martine A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250226/
https://www.ncbi.nlm.nih.gov/pubmed/37094076
http://dx.doi.org/10.1093/nar/gkad299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250226/
https://www.ncbi.nlm.nih.gov/pubmed/37094076
http://dx.doi.org/10.1093/nar/gkad299

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