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RPA engages telomeric G-quadruplexes more effectively than CST

G-quadruplexes (G4s) are a set of stable secondary structures that form within guanine-rich regions of single-stranded nucleic acids that pose challenges for DNA maintenance. The G-rich DNA sequence at telomeres has a propensity to form G4s of various topologies. The human protein complexes Replicat...

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Detalles Bibliográficos
Autores principales: Olson, Conner L, Barbour, Alexandra T, Wieser, Thomas A, Wuttke, Deborah S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250233/
https://www.ncbi.nlm.nih.gov/pubmed/37140062
http://dx.doi.org/10.1093/nar/gkad315