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LncRNA EPR regulates intestinal mucus production and protects against inflammation and tumorigenesis

The long non-coding RNA EPR is expressed in epithelial tissues, binds to chromatin and controls distinct biological activities in mouse mammary gland cells. Because of its high expression in the intestine, in this study we have generated a colon-specific conditional targeted deletion (EPR cKO) to ev...

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Detalles Bibliográficos
Autores principales: Briata, Paola, Mastracci, Luca, Zapparoli, Ettore, Caputo, Luca, Ferracci, Elisa, Silvestri, Alessandra, Garuti, Anna, Hamadou, Meriem Hadjer, Inga, Alberto, Marcaccini, Elisa, Grillo, Federica, Bucci, Gabriele, Puri, Pier Lorenzo, Beznoussenko, Galina, Mironov, Alexander, Chiacchiera, Fulvio, Gherzi, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250242/
https://www.ncbi.nlm.nih.gov/pubmed/37070602
http://dx.doi.org/10.1093/nar/gkad257