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GeoBind: segmentation of nucleic acid binding interface on protein surface with geometric deep learning

Unveiling the nucleic acid binding sites of a protein helps reveal its regulatory functions in vivo. Current methods encode protein sites from the handcrafted features of their local neighbors and recognize them via a classification, which are limited in expressive ability. Here, we present GeoBind,...

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Detalles Bibliográficos
Autores principales: Li, Pengpai, Liu, Zhi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250245/
https://www.ncbi.nlm.nih.gov/pubmed/37070217
http://dx.doi.org/10.1093/nar/gkad288