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SelSA-1, a novel HDAC inhibitor demonstrates enhanced chemotherapeutic potential by redox modulation

Colorectal cancer (CRC) is a multistep disorder resulting from genetic and epigenetic genome changes. It is the third most common malignancy in developed nations accounting for roughly 600,000 deaths annually. Persistent gut inflammation, as observed in inflammatory bowel disease (IBD), is a key ris...

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Detalles Bibliográficos
Autores principales: Garg, Ayushi, Desai, Dhimant, Bhalla, Aman, Thakur, Shalu, Rastogi, Pulkit, Kaushal, Naveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250299/
https://www.ncbi.nlm.nih.gov/pubmed/37291249
http://dx.doi.org/10.1038/s41598-023-36555-w