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DNA methyltransferase 1 deficiency improves macrophage motility and wound healing by ameliorating cholesterol accumulation

Healing of the cutaneous wound requires macrophage recruitment at the sites of injury, where chemotactic migration of macrophages toward the wound is regulated by local inflammation. Recent studies suggest a positive contribution of DNA methyltransferase 1 (Dnmt1) to macrophage pro-informatory respo...

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Detalles Bibliográficos
Autores principales: Zhao, Chuanrong, Yang, Qianru, Tang, Runze, Li, Wang, Wang, Jin, Yang, Fangfang, Zhao, Jianan, Zhu, Juanjuan, Pang, Wei, Li, Ning, Zhang, Xu, Tian, Xiao Yu, Yao, Weijuan, Zhou, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250321/
https://www.ncbi.nlm.nih.gov/pubmed/37291182
http://dx.doi.org/10.1038/s41536-023-00306-2