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Translational regulation and protein-coding capacity of the 5′ untranslated region of human TREM2

TREM2 is a transmembrane receptor expressed in microglia and macrophages. Elevated TREM2 levels in these cells are associated with age-related pathological conditions, including Alzheimer’s disease. However, the regulatory mechanism underlying the protein expression of TREM2 remains unclear. In this...

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Detalles Bibliográficos
Autores principales: Yanaizu, Motoaki, Adachi, Haruka, Araki, Makoto, Kontani, Kenji, Kino, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250343/
https://www.ncbi.nlm.nih.gov/pubmed/37291187
http://dx.doi.org/10.1038/s42003-023-04998-6