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Primary mouse myoblast metabotropic purinoceptor profiles and calcium signalling differ with their muscle origin and are altered in mdx dystrophinopathy

Mortality of Duchenne Muscular Dystrophy (DMD) is a consequence of progressive wasting of skeletal and cardiac muscle, where dystrophinopathy affects not only muscle fibres but also myogenic cells. Elevated activity of P2X7 receptors and increased store-operated calcium entry have been identified in...

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Detalles Bibliográficos
Autores principales: Róg, Justyna, Oksiejuk, Aleksandra, Górecki, Dariusz C., Zabłocki, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250391/
https://www.ncbi.nlm.nih.gov/pubmed/37291185
http://dx.doi.org/10.1038/s41598-023-36545-y