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LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma

Cancer stem cell-like cells (CSCs) play an integral role in the heterogeneity, metastasis, and treatment resistance of head and neck squamous cell carcinoma (HNSCC) due to their high tumor initiation capacity and plasticity. Here, we identified a candidate gene named LIMP-2 as a novel therapeutic ta...

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Detalles Bibliográficos
Autores principales: Liu, Yuantong, Li, Shujin, Wang, Shuo, Yang, Qichao, Wu, Zhizhong, Zhang, Mengjie, Chen, Lei, Sun, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250453/
https://www.ncbi.nlm.nih.gov/pubmed/37291150
http://dx.doi.org/10.1038/s41368-023-00229-0