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Formulation of pH-responsive highly swellable hydrogel scaffolds for controlled release of tramadol HCl: characterization and biocompatibility evaluation

Introduction: The objective of current project was to formulate a system for controlled delivery of Tramadol HCl (TRD), an opioid analgesic used in the treatment of moderate to severe pain. Methods: For this purpose, a pH responsive AvT-co-poly hydrogel network was formulated through free radical po...

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Detalles Bibliográficos
Autores principales: Abdullah, Zainab, Ashraf, Muhammad Umer, Barkat, Kashif, Badshah, Syed Faisal, Rehman, Umaira, Razzaq, Asma, Mahmood, Asif, Ulhaq, Farid, Chopra, Hitesh, Rashid, Summya, Valko, Marian, Alomar, Suliman, Kuca, Kamil, Sharma, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250648/
https://www.ncbi.nlm.nih.gov/pubmed/37304144
http://dx.doi.org/10.3389/fbioe.2023.1190322