Muscle-derived stem cell exosomes with overexpressed miR-214 promote the regeneration and repair of rat sciatic nerve after crush injury to activate the JAK2/STAT3 pathway by targeting PTEN

INTRODUCTION: This study aimed to investigate the effect of muscle-derived stem cell (MDSC) exosomes with overexpressed miR-214 on the regeneration and repair of rat sciatic nerve after crush injury and its molecular mechanism. METHODS: First, primary MDSCs, Schwann cells (SCs) and dorsal root gangl...

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Detalles Bibliográficos
Autores principales: Zeng, Xiangyu, Bian, Wei, Liu, Ziwen, Li, Jianming, Ren, Shuai, Zhang, Jian, Zhang, Haoran, Tegeleqi, Bu, He, Guanyi, Guan, Mingyan, Gao, Zewei, Huang, Chi, Liu, Jianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250677/
https://www.ncbi.nlm.nih.gov/pubmed/37305554
http://dx.doi.org/10.3389/fnmol.2023.1146329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250677/
https://www.ncbi.nlm.nih.gov/pubmed/37305554
http://dx.doi.org/10.3389/fnmol.2023.1146329

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