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Aromatic oligoesters as novel helix mimetic scaffolds

The design, synthesis, and conformational analysis of a novel aromatic oligoester helix mimetic scaffold is reported. A range of amino acid-type side-chain functionality can be readily incorporated into monomer building blocks over three facile synthetic steps. Analysis of representative dimers reve...

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Detalles Bibliográficos
Autores principales: Haque, Muhammed, Flack, Theo, Singh, Ravi, Wall, Archie, de Castro, Guilherme Vieira, Jiang, Lishen, White, Andrew J.P., Barnard, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250785/
https://www.ncbi.nlm.nih.gov/pubmed/37182518
http://dx.doi.org/10.1016/j.bmc.2023.117311