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Revolving hexameric ATPases as asymmetric motors to translocate double-stranded DNA genome along one strand

DsDNA translocation through nanoscale pores is generally accomplished by ATPase biomotors. The discovery of the revolving dsDNA translocation mechanism, as opposed to rotation, in bacteriophage phi29 elucidated how ATPase motors move dsDNA. Revolution-driven, hexameric dsDNA motors have been reporte...

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Detalles Bibliográficos
Autores principales: Bohmer, Margaret, Bhullar, Abhjeet S., Weitao, Tao, Zhang, Long, Lee, Jing-Huei, Guo, Peixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250835/
https://www.ncbi.nlm.nih.gov/pubmed/37305704
http://dx.doi.org/10.1016/j.isci.2023.106922