Intranasal or airborne transmission-mediated delivery of an attenuated SARS-CoV-2 protects Syrian hamsters against new variants

Detection of secretory antibodies in the airway is highly desirable when evaluating mucosal protection by vaccines against a respiratory virus, such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We show that intranasal delivery of an attenuated SARS-CoV-2 (Nsp1-K164A/H165A) in...

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Detalles Bibliográficos
Autores principales: Stauft, Charles B., Selvaraj, Prabhuanand, D’Agnillo, Felice, Meseda, Clement A., Liu, Shufeng, Pedro, Cyntia L., Sangare, Kotou, Lien, Christopher Z., Weir, Jerry P., Starost, Matthew F., Wang, Tony T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250859/
https://www.ncbi.nlm.nih.gov/pubmed/37296125
http://dx.doi.org/10.1038/s41467-023-39090-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250859/
https://www.ncbi.nlm.nih.gov/pubmed/37296125
http://dx.doi.org/10.1038/s41467-023-39090-4

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