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Testis cell pyroptosis mediated by CASP1 and CASP4: possible sertoli cell-only syndrome pathogenesis

BACKGROUND: Sertoli cell-only syndrome (SCOS) is the most serious pathological type of non-obstructive azoospermia. Recently, several genes related to SCOS have been identified, including FANCM, TEX14, NR5A1, NANOS2, PLK4, WNK3, and FANCA, but they cannot fully explain the pathogenesis of SCOS. This...

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Detalles Bibliográficos
Autores principales: Liu, Wantao, Li, Xinan, Ma, Qiang, Zhu, Yongtong, Zhao, Wenzhong, Yang, Yisheng, Xiao, Weiqiang, Huang, Daxiong, Cai, Fengbo, Chan, David Yiu Leung, Zhao, Shanchao, Chu, Qingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250861/
https://www.ncbi.nlm.nih.gov/pubmed/37296437
http://dx.doi.org/10.1186/s12958-023-01101-w