Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart

General control of amino acid synthesis 5-like 1 (GCN5L1) was previously identified as a key regulator of protein lysine acetylation in mitochondria. Subsequent studies demonstrated that GCN5L1 regulates the acetylation status and activity of mitochondrial fuel substrate metabolism enzymes. However,...

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Detalles Bibliográficos
Autores principales: Zhang, Manling, Feng, Ning, Peng, Zishan, Thapa, Dharendra, Stoner, Michael W., Manning, Janet R., McTiernan, Charles F., Yang, Xue, Jurczak, Michael J., Guimaraes, Danielle, Rao, Krithika, Shiva, Sruti, Kaufman, Brett A., Sack, Michael N., Scott, Iain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250906/
https://www.ncbi.nlm.nih.gov/pubmed/37305705
http://dx.doi.org/10.1016/j.isci.2023.106942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250906/
https://www.ncbi.nlm.nih.gov/pubmed/37305705
http://dx.doi.org/10.1016/j.isci.2023.106942

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