Thrombogenic potential of picomolar coagulation factor XIa is mediated by thrombin wave propagation

Inhibitors of coagulation factor XIa (FXIa) are currently being investigated as potential anticoagulant therapies. We hypothesize that circulating FXIa could be a potential target for these therapies. Using previous analyses of FXIa impurities in immune globulin products involved in thrombotic adver...

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Detalles Bibliográficos
Autores principales: Parunov, Leonid A., Liang, Yideng, Lu, Qijin, Shibeko, Alexey M., Tucker, Erik I., Lee, Timothy K., Ataullakhanov, Fazoil I., Scott, Dorothy E., Ovanesov, Mikhail V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250917/
https://www.ncbi.nlm.nih.gov/pubmed/36724509
http://dx.doi.org/10.1182/bloodadvances.2022008743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250917/
https://www.ncbi.nlm.nih.gov/pubmed/36724509
http://dx.doi.org/10.1182/bloodadvances.2022008743

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