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Basal type I interferon signaling has only modest effects on neonatal and juvenile hematopoiesis

Type I interferon (IFN-1) regulates gene expression and hematopoiesis both during development and in response to inflammatory stress. We previously showed that during development in mice, hematopoietic stem cells (HSCs) and multipotent progenitors (MPPs) induce IFN-1 target genes shortly before birt...

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Detalles Bibliográficos
Autores principales: Li, Yanan, Yang, Wei, Wang, Helen C., Patel, Riddhi M., Casey, Emily B., Denby, Elisabeth, Magee, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250919/
https://www.ncbi.nlm.nih.gov/pubmed/36724510
http://dx.doi.org/10.1182/bloodadvances.2022008595