A critical role of RUNX1 in governing megakaryocyte-primed hematopoietic stem cell differentiation

As a transcription factor in the RUNT domain core-binding factor family, RUNX1 is crucial in multiple stages of hematopoiesis, and its mutation can cause familial platelet disorder with a predisposition to acute myeloid leukemia. Previous work has established that RUNX1 is involved in the maturation...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Tu, Zhaowei, Cai, Xiongwei, Wang, Weinan, Davis, Ashely K., Nattamai, Kalpana, Paranjpe, Aditi, Dexheimer, Philip, Wu, Jianqiang, Huang, Frank Lei, Geiger, Hartmut, Huang, Gang, Zheng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250926/
https://www.ncbi.nlm.nih.gov/pubmed/36661340
http://dx.doi.org/10.1182/bloodadvances.2022008591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250926/
https://www.ncbi.nlm.nih.gov/pubmed/36661340
http://dx.doi.org/10.1182/bloodadvances.2022008591

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