The intracellular and plasma membrane pools of phosphatidylinositol-4-monophosphate control megakaryocyte maturation and proplatelet formation

BACKGROUND: Megakaryocytes (MKs) develop from hematopoietic stem cells after stimulation by the cytokine thrombopoietin. During megakaryopoiesis, MKs enlarge, undergo the process of endomitosis, and develop intracellular membranes (demarcation membrane system, DMS). During DMS formation, there is ac...

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Detalles Bibliográficos
Autores principales: Bura, Ana, Čabrijan, Sara, Bertović, Ivana, Jurak Begonja, Antonija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251075/
https://www.ncbi.nlm.nih.gov/pubmed/37304829
http://dx.doi.org/10.1016/j.rpth.2023.100169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251075/
https://www.ncbi.nlm.nih.gov/pubmed/37304829
http://dx.doi.org/10.1016/j.rpth.2023.100169

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