RNA binding by the glucocorticoid receptor attenuates dexamethasone-induced gene activation

The glucocorticoid receptor (GR) is a ligand-activated transcription factor that regulates a suite of genes through direct binding of GR to specific DNA promoter elements. GR also interacts with RNA, but the function of this RNA-binding activity remains elusive. Current models speculate that RNA cou...

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Detalles Bibliográficos
Autores principales: Lammer, Nickolaus C., Ashraf, Humza M., Ugay, Daniella A., Spencer, Sabrina L., Allen, Mary A., Batey, Robert T., Wuttke, Deborah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251336/
https://www.ncbi.nlm.nih.gov/pubmed/37296231
http://dx.doi.org/10.1038/s41598-023-35549-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251336/
https://www.ncbi.nlm.nih.gov/pubmed/37296231
http://dx.doi.org/10.1038/s41598-023-35549-y

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