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RNA binding by the glucocorticoid receptor attenuates dexamethasone-induced gene activation
The glucocorticoid receptor (GR) is a ligand-activated transcription factor that regulates a suite of genes through direct binding of GR to specific DNA promoter elements. GR also interacts with RNA, but the function of this RNA-binding activity remains elusive. Current models speculate that RNA cou...
Autores principales: | Lammer, Nickolaus C., Ashraf, Humza M., Ugay, Daniella A., Spencer, Sabrina L., Allen, Mary A., Batey, Robert T., Wuttke, Deborah S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251336/ https://www.ncbi.nlm.nih.gov/pubmed/37296231 http://dx.doi.org/10.1038/s41598-023-35549-y |
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