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Assessment of tumor microenvironment expression and clinical significance of immune inhibitory molecule CTLA-4, ligand B7-1, and tumor-infiltrating regulatory cells in Hodgkin lymphoma
Classical Hodgkin lymphoma represents a paradigm of tumor cell–microenvironment interactions as the neoplastic Hodgkin Reed–Sternberg (HRS) cells typically constitute less than 1% of the total tumor volume. CTLA-4, a member of the CD28/B7 immunoglobulin superfamily, and CD28 and their ligands B7-1 a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Carol Davila University Press
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251379/ https://www.ncbi.nlm.nih.gov/pubmed/37305822 http://dx.doi.org/10.25122/jml-2023-0019 |