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Assessment of tumor microenvironment expression and clinical significance of immune inhibitory molecule CTLA-4, ligand B7-1, and tumor-infiltrating regulatory cells in Hodgkin lymphoma

Classical Hodgkin lymphoma represents a paradigm of tumor cell–microenvironment interactions as the neoplastic Hodgkin Reed–Sternberg (HRS) cells typically constitute less than 1% of the total tumor volume. CTLA-4, a member of the CD28/B7 immunoglobulin superfamily, and CD28 and their ligands B7-1 a...

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Detalles Bibliográficos
Autores principales: Verma, Radhey Shyam, Singh, Gyanendra, Singh, Anurag, Singh, Pradyuman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251379/
https://www.ncbi.nlm.nih.gov/pubmed/37305822
http://dx.doi.org/10.25122/jml-2023-0019