Cargando…

Synergistic effect of endurance training and nettle leaf extract on the IDO1-KYN-AHR pathway homeostasis and inhibiting of liver toxicity in rats with STZ-induced diabetes

INTRODUCTION: Diabetes adversely affects a number of hepatic molecular pathways, including the kynurenine (KYN) pathway. KYN is produced by indoleamine 2,3-dioxygenase (IDO) and activates the aryl hydrocarbon receptor (AHR). This study evaluated the effect of endurance training (EndTr) and nettle le...

Descripción completa

Detalles Bibliográficos
Autores principales: Haghshenas, Rouhollah, Aftabi, Younes, Doaei, Saied, Gholamalizadeh, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251405/
https://www.ncbi.nlm.nih.gov/pubmed/37305057
http://dx.doi.org/10.3389/fendo.2023.1071424