Development of a Novel σ(1) Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells

[Image: see text] The σ(1) receptor (S1R) is a ligand-regulated non-opioid intracellular receptor involved in several pathological conditions. The development of S1R-based drugs as therapeutic agents is a challenge due to the lack of simple functional assays to identify and classify S1R ligands. We...

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Detalles Bibliográficos
Autores principales: Morató, Xavier, Fernández-Dueñas, Víctor, Pérez-Villamor, Pilar, Valle-León, Marta, Vela, José Miguel, Merlos, Manuel, Burgueño, Javier, Ciruela, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251476/
https://www.ncbi.nlm.nih.gov/pubmed/37191585
http://dx.doi.org/10.1021/acschemneuro.3c00206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251476/
https://www.ncbi.nlm.nih.gov/pubmed/37191585
http://dx.doi.org/10.1021/acschemneuro.3c00206

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