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Development of a Novel σ(1) Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells
[Image: see text] The σ(1) receptor (S1R) is a ligand-regulated non-opioid intracellular receptor involved in several pathological conditions. The development of S1R-based drugs as therapeutic agents is a challenge due to the lack of simple functional assays to identify and classify S1R ligands. We...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251476/ https://www.ncbi.nlm.nih.gov/pubmed/37191585 http://dx.doi.org/10.1021/acschemneuro.3c00206 |