Ultrafast Fragment Screening Using Photo-Hyperpolarized (CIDNP) NMR

[Image: see text] While nuclear magnetic resonance (NMR) is regarded as a reference in fragment-based drug design, its implementation in a high-throughput manner is limited by its lack of sensitivity resulting in long acquisition times and high micromolar sample concentrations. Several hyperpolariza...

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Detalles Bibliográficos
Autores principales: Torres, Felix, Bütikofer, Matthias, Stadler, Gabriela R., Renn, Alois, Kadavath, Harindranath, Bobrovs, Raitis, Jaudzems, Kristaps, Riek, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251509/
https://www.ncbi.nlm.nih.gov/pubmed/37227050
http://dx.doi.org/10.1021/jacs.3c01392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251509/
https://www.ncbi.nlm.nih.gov/pubmed/37227050
http://dx.doi.org/10.1021/jacs.3c01392

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