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Collaborative cross strain CC011/UncJ as a novel mouse model of T2-high, severe asthma

Among asthmatics, there is significant heterogeneity in the clinical presentation and underlying pathophysiological mechanisms, leading to the recognition of multiple disease endotypes (e.g., T2-high vs. T2-low). This heterogeneity extends to severe asthmatics, who may struggle to control symptoms e...

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Detalles Bibliográficos
Autores principales: Donoghue, Lauren J., McFadden, Kathryn M., Vargas, Daniel, Smith, Gregory J., Immormino, Robert M., Moran, Timothy P., Kelada, Samir N. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251525/
https://www.ncbi.nlm.nih.gov/pubmed/37296458
http://dx.doi.org/10.1186/s12931-023-02453-y