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Effect of propranolol and clonidine after severe traumatic brain injury: a pilot randomized clinical trial

OBJECTIVE: To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade with propranolol and clonidine in patients with severe traumatic brain injury (TBI). BACKGROUND: Administration of adrenergic blockade after severe TBI is common. To date, no prospective trial has rigorously...

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Detalles Bibliográficos
Autores principales: Nordness, Mina F., Maiga, Amelia W., Wilson, Laura D., Koyama, Tatsuki, Rivera, Erika L., Rakhit, Shayan, de Riesthal, Michael, Motuzas, Cari L., Cook, Madison R., Gupta, Deepak K., Jackson, James C., Williams Roberson, Shawniqua, Meurer, William J., Lewis, Roger J., Manley, Geoffrey T., Pandharipande, Pratik P., Patel, Mayur B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251526/
https://www.ncbi.nlm.nih.gov/pubmed/37296432
http://dx.doi.org/10.1186/s13054-023-04479-6