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Transcriptomic and functional analysis of ANGPTL4 overexpression in pancreatic cancer nominates targets that reverse chemoresistance

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers based on five-year survival rates. Genes contributing to chemoresistance represent novel therapeutic targets that can improve treatment response. Increased expression of ANGPTL4 in tumors correlates with poor outcome...

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Detalles Bibliográficos
Autores principales: Gordon, Emily R., Wright, Carter A., James, Mikayla, Cooper, Sara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251551/
https://www.ncbi.nlm.nih.gov/pubmed/37291514
http://dx.doi.org/10.1186/s12885-023-11010-1