Analysis of AT7519 as a pro-resolution compound in an acetaminophen-induced mouse model of acute inflammation by UPLC-MS/MS

BACKGROUND: Uncontrolled inflammation contributes to the progression of organ damage in acute conditions, such as acetaminophen-induced acute liver injury (APAP-ALI) and there are limited treatments for this condition. AT7519, a cyclic-dependent kinase inhibitor (CDKI), has been used successfully in...

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Detalles Bibliográficos
Autores principales: Cartwright, Jennifer A., Simpson, Joanna P., Homer, Natalie Z. M., Rossi, Adriano G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251596/
https://www.ncbi.nlm.nih.gov/pubmed/37291548
http://dx.doi.org/10.1186/s12950-023-00345-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10251596/
https://www.ncbi.nlm.nih.gov/pubmed/37291548
http://dx.doi.org/10.1186/s12950-023-00345-y

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